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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCI
All Species:
42.66
Human Site:
S591
Identified Species:
67.03
UniProt:
P41743
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41743
NP_002731.4
596
68262
S591
Y
I
N
P
L
L
M
S
A
E
E
C
V
_
_
Chimpanzee
Pan troglodytes
XP_001148501
597
67369
S592
Y
I
N
P
L
L
L
S
T
E
E
S
V
_
_
Rhesus Macaque
Macaca mulatta
XP_001089400
597
68263
S592
Y
I
N
P
L
L
M
S
A
E
E
C
V
_
_
Dog
Lupus familis
XP_535855
696
78257
S691
Y
I
N
P
L
L
M
S
A
E
E
C
V
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q62074
595
68185
S590
Y
I
N
P
L
L
M
S
A
E
E
C
V
_
_
Rat
Rattus norvegicus
P09217
592
67715
S587
Y
I
N
P
L
L
L
S
A
E
E
S
V
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506164
360
41199
Chicken
Gallus gallus
XP_417561
606
69931
S601
Y
I
N
P
L
L
L
S
T
E
E
T
V
_
_
Frog
Xenopus laevis
NP_001084068
588
67442
S583
Y
I
N
P
L
L
M
S
A
E
E
C
V
_
_
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
S583
Y
I
N
P
L
L
M
S
A
E
E
C
V
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
P629
F
V
N
P
K
F
G
P
E
R
K
V
Y
_
_
Honey Bee
Apis mellifera
XP_397273
590
68031
S585
Y
V
N
P
L
L
M
S
L
E
D
C
V
_
_
Nematode Worm
Caenorhab. elegans
Q19266
597
68017
S592
Y
V
N
P
L
Q
M
S
R
E
D
S
V
_
_
Sea Urchin
Strong. purpuratus
XP_780275
524
59689
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Y1137
E
E
F
R
G
F
S
Y
T
A
D
F
E
_
_
Conservation
Percent
Protein Identity:
100
66.6
96.8
84.3
N.A.
98.3
72.3
N.A.
59.9
71.4
89.7
88.7
N.A.
36.4
67.9
58.1
63.5
Protein Similarity:
100
78.5
97.4
84.9
N.A.
98.8
83.5
N.A.
60.4
83
94.4
92.9
N.A.
54
78.1
74.1
72.4
P-Site Identity:
100
76.9
100
100
N.A.
100
84.6
N.A.
0
76.9
100
100
N.A.
15.3
76.9
61.5
0
P-Site Similarity:
100
84.6
100
100
N.A.
100
92.3
N.A.
0
84.6
100
100
N.A.
38.4
92.3
76.9
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
23.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
7.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
47
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% D
% Glu:
7
7
0
0
0
0
0
0
7
74
60
0
7
0
0
% E
% Phe:
7
0
7
0
0
14
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% K
% Leu:
0
0
0
0
74
67
20
0
7
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
54
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
80
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
7
7
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
74
0
0
0
20
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
20
0
0
7
0
0
0
% T
% Val:
0
20
0
0
0
0
0
0
0
0
0
7
74
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
74
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
87
87
% _